Systemic inflammation and lung function
نویسندگان
چکیده
منابع مشابه
Systemic inflammation, genetic susceptibility and lung function.
Local inflammation in airway diseases is well recognised, but less is known about the association between low-grade systemic inflammatory processes and lung function. The aim of the present study was to assess the association between inflammatory markers and lung function, taking into account polymorphisms in genes coding for inflammatory markers. In 134 post-myocardial infarction patients, six...
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BACKGROUND Impaired lung function is associated with systemic inflammation and is a risk factor for cardiovascular disease in older adults. It is unknown when these associations emerge and to what extent they are mediated by smoking, chronic airways disease, and/or established atherosclerosis. We explored the association between the forced expiratory volume in one second (FEV(1)) and the system...
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Nuclear factor-κB (NF-κB) is a nuclear transcription factor first recognized in 1986 by Sen and Baltimore. Its name derives from the fact that it was first diagnosed in the nuclei of B cells [13] bound to an enhancer element of the immunoglobulin kappa light chain gene [4]. At that time, NF-κB was primarily thought to be a B-cell–specific transcription factor, but it was afterward found to be p...
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Systemic maternal inflammation contributes to preterm birth and is associated with development of bronchopulmonary dysplasia (BPD). Infants with BPD exhibit decreased alveolarization, diffuse interstitial fibrosis with thickened alveolar septa, and impaired pulmonary function. We tested the hypothesis that systemic prenatal LPS administration to pregnant mice followed by postnatal hyperoxia exp...
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BACKGROUND Obesity and asthma are associated. There is a relationship between lung function impairment and the metabolic syndrome. Whether this relationship also exists in the morbidly obese patients is still unknown. Hypothesis. Low-grade systemic inflammation associated with the metabolic syndrome causes inflammation in the lungs and, hence, lung function impairment. METHODS This is cross-s...
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ژورنال
عنوان ژورنال: The Clinical Respiratory Journal
سال: 2011
ISSN: 1752-6981
DOI: 10.1111/j.1752-699x.2011.00266_7.x